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Funder: European Commission – Horizon Europe (Cluster 1: Health)

Link: Horizon Europe Work Programme – (Pre-publication)

Submission Model: Single-stage submission process

Submission Deadline for Pre-Proposals: 16 September 2025 17:00:00 Brussels time, check the Funding & Tenders Portal for updates.

Budget: Total indicative budget: €30 million; Expected EU contribution per project: ~€6 million

Aims / Objectives:

This call aims to fund research addressing high-burden, under-researched medical conditions (not including rare diseases, rare cancers, and under-researched medical conditions already addressed by projects funded under the HORIZON-HLTH-2024-DISEASE-03-14-two-stage). The goal is to improve understanding, diagnosis, treatment, and prevention of these conditions through multidisciplinary, patient-inclusive, and translational approaches. The expected outcomes include:

  1. The scientific and clinical community:
    • make effective use of state-of-the-art information, data, technologies, tools and best practices to better understand the condition, underpinning the development of diagnostics, therapeutics and/or preventive strategies;
    • exchange data, knowledge and best practices, thereby strengthening their collaboration and building knowledge and care networks in Europe and beyond;
    • make wide use of newly established and, where relevant, open access databases and/or integrate them with existing infrastructures for storage and sharing of collected data according to FAIR[1] principles, thereby encouraging further use of the data.
  2. Policymakers and funders are informed of the research advances made, and consider further support in light of the sustainability of the studies.
  3. Patients and caregivers are constructively engaged with the research, which also caters for their needs.
  4. Health professionals have access to and use improved clinical guidelines on diagnosis and/or treatment of the condition.

Relevance to the pain community:

This funding call is highly relevant to the pain research community, as it explicitly invites projects focused on conditions that are prevalent, complex, and often inadequately treated, including chronic pain-related disorders. It offers an opportunity to advance scientific knowledge, clinical practice, and patient outcomes by addressing persistent gaps in the understanding and management of pain within a broad health research framework.

 

Include EFIC as a partner in your research consortia/grant applications

Effective communication of results and societal/clinical impact are increasingly emphasised by research funding bodies. EFIC can help your research project achieve this and more through doing the following:

  • Communicate your research project results and updates via EFIC’s online communication channels – social media, mailing list, website
  • Produce and share video interviews about your research
  • Host open webinars on your research
  • Connect you to the programme organisers for our scientific meetings, where you may be offered the opportunity to showcase your research
  • Provide access to our database of 20,000 clinicians and researchers, including for survey participation.
  • Recruit subject matter experts through our ‘Pain Scientist Network’
  • Patient and public involvement; Involve = patients and other stakeholders in your research through our strong links with patients’ organisations and experience in lay-audience communication
  • Boost your network through engaging with our established connections with scientific societies, industry, patients’ organisations and policy makers.

Please contact sam.kynman@efic.org for more information on how EFIC could contribute.

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